Abstract | OBJECTIVE: PATIENTS AND METHODS: This was a population study of Olmsted County residents with hypertensive crisis between January 1, 2000, and December 31, 2008, with follow-up until June 30, 2016. RESULTS: The results demonstrated that those with underlying chronic kidney disease upon admission for hypertensive crisis, defined as a systolic blood pressure above 180 mm Hg or diastolic blood pressure above 120 mm Hg, were more likely to develop acute kidney injury during hospitalization (odds ratio, 6.04; 95% CI, 1-26; P=.02). Hospitalization length of stay was increased when patients developed acute kidney injury during hypertensive crisis hospitalization (7.6±9 vs 3.4±4 days; P=.04). Furthermore, those who developed acute kidney injury had increased cardiac rehospitalization frequency over 10 years (87% vs 46%; P=.009). These results suggest that those with poor renal reserve are more likely to have further acute kidney damage in the setting of hypertensive crisis, likely due to decreased renal perfusion and neurohormonal dysregulation. CONCLUSION:
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Authors | Siu-Hin Wan, Joshua P Slusser, David O Hodge, Horng H Chen |
Journal | Mayo Clinic proceedings. Innovations, quality & outcomes
(Mayo Clin Proc Innov Qual Outcomes)
Vol. 2
Issue 2
Pg. 148-154
(Jun 2018)
ISSN: 2542-4548 [Electronic] Netherlands |
PMID | 30225444
(Publication Type: Journal Article)
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