Neoplasia in Three Aye-Ayes (Daubentonia madagascariensis).

Abstract

Tumours diagnosed in three aged captive aye-ayes (Daubentonia madagascariensis), held in two different institutions, are described. A cerebral glioblastoma was diagnosed based on histological and immunohistochemical findings in one of the animals following initial presentation with bilateral mydriasis, absent pupillary reflex, head tilt and ataxia. A second animal was humanely destroyed due to impaired locomotion associated with spondylosis and a post-mortem diagnosis of cholangiocarcinoma was made based on histology with further confirmation with immunohistochemical labelling for cytokeratin 7. A third aye-aye suffering from dental disease was diagnosed with an oral squamous cell carcinoma following an excisional biopsy from a non-healing wound in the lip. Due to progression of the neoplasia the animal was humanely destroyed and post-mortem examination revealed the presence on an additional unilateral phaeochromocytoma.

• Authors: A Rodriguez Barbon, R Cowen, C Knott, K Hughes, K Allinson, C V Williams, A Routh
• Journal: Journal of comparative pathology (J Comp Pathol) Vol. 159 Pg. 16-20 (Feb 2018) ISSN: 1532-3129 [Electronic] England
• PMID: 29599000 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2017 Elsevier Ltd. All rights reserved.

Topics

• Animals
• Female
• Male
• Neoplasms (veterinary)
• Strepsirhini