DYNAMIC RETINA VESSEL COLOR CHANGE DURING OCULAR COMPRESSION IN SEVERE LIPEMIA RETINALIS.

Abstract

PURPOSE:

The aim of this study was to describe dynamic color change in retinal vessels from white to coral pink due to externally applied ocular pressure in a 6-week-old infant with lipemia retinalis secondary to type 1b familial hyperlipoproteinemia.

METHODS:

Fundus images and fluorescein angiogram were taken with RetCam3 camera. Color photographs of pooled blood were taken during phlebotomy.

RESULTS:

Genetic analysis revealed a rare genetic mutation in the APOC2 gene, a lipoprotein lipase activator. Intraocular pressure applied to the globe induced a color change in the retinal arteries from white to coral pink. Disruption in laminar flow leading to this change is described.

CONCLUSION:

This is the first report to attribute the retinal vessel color change to disrupted laminar flow and the intermixing of larger erythrocytes and smaller chylomicrons in a patient with lipemia retinalis. In addition, this is a rare example of congenital hyperlipidemia in the offspring of nonconsanguineous parents.

• Authors: Maria Benson, Robert W Wong, Ryan C Young, James B Gibson, Yuxin Fan, Clio Armitage Harper 3rd
• Journal: Retinal cases & brief reports (Retin Cases Brief Rep) 2018 Fall Vol. 12 Suppl 1 Pg. S98-S101 ISSN: 1937-1578 [Electronic] United States
• PMID: 29283911 (Publication Type: Case Reports, Journal Article)

Topics

• Color
• Female
• Humans
• Hyperlipidemias (blood, complications)
• Infant
• Retinal Diseases (blood, diagnostic imaging, etiology)
• Retinal Vessels (diagnostic imaging)