[Consensus-Based Guidelines for Diagnosis, Prevention and Treatment of Tuberculosis in Children and Adolescents - A Guideline on Behalf of the German Society for Pediatric Infectious Diseases (DGPI)].

Abstract	Recently, epidemiological data shows an increase of childhood tuberculosis in Germany. In addition to this, drug resistant tuberculosis becomes more frequent. Therefore, diagnosis, prevention and therapy in childhood and adolescence remain a challenge. Adult guidelines do not work for children, as there are age specific differences in manifestation, risk of progression and diagnostic as well as therapeutic pathways.The German Society for Pediatric Infectious Diseases (DGPI) has initiated a consensus-based (S2k) process and completed a paediatric guideline in order to improve and standardize care for children and adolescents with tuberculosis exposure, infection or disease.Updated dosage recommendations take age dependant pharmacokinetics in the treatment of drug sensitive but also drug resistant tuberculosis in account. In addition to this, there is a detailed chapter on perinatal exposure and disease as well as extrapulmonary manifestations.
Authors	C Feiterna-Sperling, F Brinkmann, C Adamczick, F Ahrens, M Barker, C Berger, L D Berthold, M Bogyi, U von Both, T Frischer, W Haas, P Hartmann, D Hillemann, F W Hirsch, K Kranzer, F Kunitz, E Maritz, A Pizzulli, N Ritz, R Schlags, T Spindler, S Thee, K Weizsäcker
Journal	Pneumologie (Stuttgart, Germany) (Pneumologie) Vol. 71 Issue 10 Pg. 629-680 (Oct 2017) ISSN: 1438-8790 [Electronic] Germany
Vernacular Title	S2k-Leitlinie zur Diagnostik, Prävention und Therapie der Tuberkulose im Kindes- und Jugendalter.
PMID	29017219 (Publication Type: Consensus Development Conference, Journal Article, Practice Guideline)
Copyright	© Georg Thieme Verlag KG Stuttgart · New York.
Chemical References	Antitubercular Agents
Topics	Adolescent Antitubercular Agents (therapeutic use) Austria Child Child, Preschool Cross-Sectional Studies Female Germany Humans Infant Infant, Newborn Infectious Disease Medicine Male Pediatrics Societies, Medical Switzerland Tuberculosis, Multidrug-Resistant (diagnosis, drug therapy, epidemiology, prevention & control) Tuberculosis, Pulmonary (diagnosis, drug therapy, epidemiology, prevention & control)

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