Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme content and delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells.

• Authors: P S Ebert, R A Hess, B C Frykholm, D P Tschudy
• Journal: Biochemical and biophysical research communications (Biochem Biophys Res Commun) Vol. 88 Issue 4 Pg. 1382-90 (Jun 27 1979) ISSN: 0006-291X [Print] United States
• PMID: 289386 (Publication Type: Journal Article)

Chemical References

• Hemoglobins
• Heptanoates
• Heptanoic Acids
• Keto Acids
• Heme
• succinylacetone
• Porphobilinogen Synthase

Topics

• Animals
• Cell Division (drug effects)
• Cells, Cultured
• Heme (biosynthesis)
• Hemoglobins (biosynthesis)
• Heptanoates (pharmacology)
• Heptanoic Acids (pharmacology)
• Keto Acids (pharmacology)
• Leukemia, Erythroblastic, Acute (metabolism)
• Leukemia, Experimental (metabolism)
• Mice
• Porphobilinogen Synthase (antagonists & inhibitors)