Efficacy of the Perfluoro-N-Octane-Assisted Single-Layered Inverted Internal Limiting Membrane Flap Technique for Large Macular Holes.

Abstract

PURPOSE:

The aim of this study was to evaluate the efficacy of the perfluoro-n-octane-assisted single-layered inverted internal limiting membrane (ILM) flap for large macular holes (MHs).

METHODS:

We reviewed idiopathic MHs >400 μm. The patients were divided into ILM peeling (group P, 51 eyes) and ILM flap (group F, 41 eyes). Closure of MHs, best-corrected visual acuity (BCVA), and postoperative optical coherence tomography findings were analyzed.

RESULTS:

MH closure was achieved in 88.2% in group P and in 100% in group F (p = 0.032). SF6 and air was used most frequently in groups P and F, respectively. Both had a significant improvement in BCVA, which was better in group F until 3 months, but not at 6 months. At 6 months, the ellipsoid zone and external limiting membrane were restored with no significant difference.

CONCLUSION:

The single-layered inverted ILM flap was better for the closure of large MHs than ILM peeling, without using long-acting gas that prevents early rehabilitation.

• Authors: Kang Yeun Pak, Jung Yul Park, Sung Who Park, Ik Soo Byon, Ji Eun Lee
• Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde (Ophthalmologica) Vol. 238 Issue 3 Pg. 133-138 ( 2017) ISSN: 1423-0267 [Electronic] Switzerland
• PMID: 28715813 (Publication Type: Journal Article)
• Copyright: © 2017 S. Karger AG, Basel.

Chemical References

• Fluorocarbons
• perfluorooctane

Topics

• Aged
• Basement Membrane (surgery)
• Female
• Fluorocarbons (pharmacology)
• Follow-Up Studies
• Humans
• Male
• Retinal Perforations (diagnosis, surgery)
• Retrospective Studies
• Surgical Flaps
• Tomography, Optical Coherence
• Treatment Outcome
• Visual Acuity
• Vitrectomy (methods)