[Therapeutic Strategies with Multidisciplinary Local Therapy for Postoperative Recurrence of Esophageal Cancer].

Abstract

We report our experience with tailored treatment comprising resection or radiotherapy for postoperative recurrence of esophageal cancer in 73 patients(35.4%)who were diagnosed with recurrent esophageal cancer after curative resection. The initial recurrence patterns included 7 patients(3.4%)with local recurrence, 38 patients(18.4%)with lymphatic recurrence, 40 patients(19.4%)with hematologic metastases, and 12 patients(5.8%)with dissemination.Twenty -three patients had solitary lung metastases, and good local control was achieved by surgical resection alone.The success rate of intensity modulated radiation therapy (IMRT) for local control was 64.1%, and IMRT was considered effective and less invasive. The 2-year survival rate after successful treatment for recurrence was 53.5%, vs 5.8% after unsuccessful treatment. Improved prognosis for patients with recurrent esophageal cancer can be expected when adequate local control is achieved according to recurrence pattern by surgical resection or IMRT.

• Authors: Koichi Okamoto, Itasu Ninomiya, Atsushi Hirose, Jun Kinoshita, Keishi Nakamura, Katsunobu Oyama, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Sachio Fushida, Tsuyoshi Takanaka, Tetsuo Ohta
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 43 Issue 12 Pg. 1490-1492 (Nov 2016) ISSN: 0385-0684 [Print] Japan
• PMID: 28133033 (Publication Type: Journal Article)

Topics

• Aged
• Combined Modality Therapy
• Esophageal Neoplasms (diagnosis, pathology, therapy)
• Female
• Humans
• Lung Neoplasms (secondary, surgery)
• Male
• Postoperative Period
• Prognosis
• Recurrence