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Dasatinib and allogeneic stem cell transplantation enable sustained response in an elderly patient with RCSD1-ABL1-positive acute lymphoblastic leukemia.

AuthorsMiriam Frech, Lutz B Jehn, Kathleen Stabla, Stephan Mielke, Björn Steffen, Hermann Einsele, Stephan K Metzelder, Andreas Neubauer
JournalHaematologica (Haematologica) Vol. 102 Issue 4 Pg. e160-e162 (04 2017) ISSN: 1592-8721 [Electronic] Italy
PMID28057740 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • Antineoplastic Agents
  • Intracellular Signaling Peptides and Proteins
  • Oncogene Proteins, Fusion
  • RCSD1 protein, human
  • Proto-Oncogene Proteins c-abl
  • Dasatinib
Topics
  • Antineoplastic Agents (therapeutic use)
  • Base Sequence
  • Dasatinib (therapeutic use)
  • Female
  • Gene Expression
  • Hematopoietic Stem Cell Transplantation
  • Humans
  • Intracellular Signaling Peptides and Proteins (genetics, metabolism)
  • Middle Aged
  • Oncogene Proteins, Fusion (antagonists & inhibitors, genetics, metabolism)
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma (genetics, metabolism, pathology, therapy)
  • Proto-Oncogene Proteins c-abl (antagonists & inhibitors, genetics, metabolism)
  • Translocation, Genetic
  • Transplantation, Homologous
  • Treatment Outcome

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