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Phase II trials of flavone acetic acid in advanced malignant melanoma and colorectal carcinoma.

Abstract
Flavone acetic acid (FAA), 8.6 gm-2 has been administered by 6h intravenous infusion to 19 patients with advanced colorectal carcinoma and 15 patients with advanced malignant melanoma. The drug associated toxicity was generally mild and as predicted from the phase I study. No responses were seen in either disease.
AuthorsD J Kerr, T Maughan, E Newlands, G Rustin, N M Bleehen, C Lewis, S B Kaye
JournalBritish journal of cancer (Br J Cancer) Vol. 60 Issue 1 Pg. 104-6 (Jul 1989) ISSN: 0007-0920 [Print] England
PMID2803908 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antineoplastic Agents
  • Flavonoids
  • flavone acetic acid
Topics
  • Adult
  • Aged
  • Antineoplastic Agents (adverse effects, therapeutic use)
  • Colorectal Neoplasms (drug therapy)
  • Drug Evaluation
  • Female
  • Flavonoids (adverse effects, therapeutic use)
  • Humans
  • Male
  • Melanoma (drug therapy)
  • Middle Aged

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