Anticestodal action of oxfendazole on Raillietina tetragona in experimentally infected chickens.

Abstract

Oxfendazole was tested against Raillietina tetragona in experimentally infected chickens using single oral doses of 20, 10, 7.5, 5, and 2.5 mg/kg body weight. The minimal dose of the drug which produced 100% efficacy against immature worms was 10 mg/kg whereas the same effect on the mature parasite was obtained with 7.5 mg/kg. Doses lower than these significantly reduce worm burdens. The compound appears to be safe for chickens and a dose of 20 mg/kg (twice the recommended dose) produced no untoward clinical reactions.

• Authors: I E Nurelhuda, E E Elowni, T Hassan
• Journal: The British veterinary journal (Br Vet J) 1989 Sep-Oct Vol. 145 Issue 5 Pg. 458-61 ISSN: 0007-1935 [Print] England
• PMID: 2790437 (Publication Type: Journal Article)

Chemical References

• Anticestodal Agents
• Benzimidazoles
• oxfendazole

Topics

• Animals
• Anticestodal Agents (therapeutic use)
• Benzimidazoles (therapeutic use)
• Cestode Infections (drug therapy, veterinary)
• Chickens (parasitology)
• Poultry Diseases (drug therapy)