Diabetes increases the risk of an appendectomy in patients with antibiotic treatment of noncomplicated appendicitis.

Abstract

BACKGROUND:

This retrospective cohort study examined whether diabetic patients have a higher risk for recurrent appendicitis during a 1-year follow-up period after successful antibiotic treatment for patients with acute uncomplicated appendicitis than nondiabetic patients using a population-based database.

METHODS:

We included 541 appendicitis patients who received antibiotic treatment for acute appendicitis. We individually tracked each patient for a 1-year period to identify those who subsequently underwent an appendectomy during the follow-up period.

RESULTS:

Cox proportional hazard regressions suggested that the adjusted hazard ratio of an appendectomy during the 1-year follow-up period was 1.75 for appendicitis patients with diabetes than appendicitis patients without diabetes. We found that among females, the adjusted hazard ratio of an appendectomy was 2.18 for acute appendicitis patients with diabetes than their counterparts without diabetes. However, we failed to observe this relationship in males.

CONCLUSIONS:

We demonstrated a relationship between diabetes and a subsequent appendectomy in females who underwent antibiotic treatment for noncomplicated appendicitis.

• Authors: Ming-Chieh Tsai, Herng-Ching Lin, Cha-Ze Lee
• Journal: American journal of surgery (Am J Surg) Vol. 214 Issue 1 Pg. 24-28 (Jul 2017) ISSN: 1879-1883 [Electronic] United States
• PMID: 27616688 (Publication Type: Journal Article)
• Copyright: Copyright © 2016 Elsevier Inc. All rights reserved.

Chemical References

• Anti-Bacterial Agents

Topics

• Anti-Bacterial Agents (therapeutic use)
• Appendectomy (statistics & numerical data)
• Appendicitis (epidemiology, therapy)
• Cohort Studies
• Diabetes Mellitus (epidemiology)
• Female
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Retrospective Studies
• Risk
• Sex Factors
• Taiwan (epidemiology)