Radiotherapy of Cervical Cancer.

Abstract

Curative-intent radical radiotherapy of cervical cancer consists of external-beam radiotherapy, brachytherapy, and concomitant chemotherapy with cisplatin. For each element, new developments aim to improve tumor control rates or treatment tolerance. Intensity-modulated radiotherapy (IMRT) has been shown to reduce gastrointestinal toxicity and can be used to selectively increase the radiotherapy dose. Individualized, image-guided brachytherapy enables better adaptation of high-dose volumes to the tumor extension. Intensification of concomitant or sequential systemic therapy is under evaluation.

• Authors: Dirk Vordermark
• Journal: Oncology research and treatment (Oncol Res Treat) Vol. 39 Issue 9 Pg. 516-20 ( 2016) ISSN: 2296-5262 [Electronic] Switzerland
• PMID: 27614991 (Publication Type: Journal Article, Review)
• Copyright: © 2016 S. Karger GmbH, Freiburg.

Topics

• Brachytherapy (adverse effects, methods)
• Combined Modality Therapy (methods)
• Evidence-Based Medicine
• Female
• Gastrointestinal Diseases (etiology, prevention & control)
• Germany
• Humans
• Radiation Injuries (etiology, prevention & control)
• Radiotherapy Dosage
• Radiotherapy, Conformal (adverse effects, methods)
• Radiotherapy, Image-Guided (adverse effects, methods)
• Treatment Outcome
• Uterine Cervical Neoplasms (diagnosis, radiotherapy)