High-Resolution MRI Findings following Trigeminal Rhizotomy.

Abstract

BACKGROUND AND PURPOSE:

Patients with trigeminal neuralgia often undergo trigeminal rhizotomy via radiofrequency thermocoagulation or glycerol injection for treatment of symptoms. To date, radiologic changes in patients with trigeminal neuralgia post-rhizotomy have not been described, to our knowledge. The aim of this study was to evaluate patients after trigeminal rhizotomy to characterize post-rhizotomy changes on 3D high-resolution MR imaging.

MATERIALS AND METHODS:

A retrospective review of trigeminal neuralgia protocol studies was performed in 26 patients after rhizotomy compared with 54 treatment-naïve subjects with trigeminal neuralgia. Examinations were reviewed independently by 2 neuroradiologists blinded to the side of symptoms and treatment history. The symmetry of Meckel's cave on constructive interference in steady-state and the presence of contrast enhancement within the trigeminal nerves on volumetric interpolated breath-hold examination images were assessed subjectively. The signal intensity of Meckel's cave was measured on coronal noncontrast constructive interference in steady-state imaging on each side.

RESULTS:

Post-rhizotomy changes included subjective clumping of nerve roots and/or decreased constructive interference in steady-state signal intensity within Meckel's cave, which was identified in 17/26 (65%) patients after rhizotomy and 3/54 (6%) treatment-naïve patients (P < .001). Constructive interference in steady-state signal intensity within Meckel's cave was, on average, 13% lower on the side of the rhizotomy in patients posttreatment compared with a 1% difference in controls (P < .001). Small regions of temporal encephalomalacia were noted in 8/26 (31%) patients after rhizotomy and 0/54 (0%) treatment-naïve patients (P < .001).

CONCLUSIONS:

Post-trigeminal rhizotomy findings frequently include nerve clumping and decreased constructive interference in steady-state signal intensity in Meckel's cave. Small areas of temporal lobe encephalomalacia are encountered less frequently.

• Authors: B G Northcutt, D P Seeburg, J Shin, N Aygun, D A Herzka, D Theodros, C R Goodwin, C Bettegowda, M Lim, A M Blitz
• Journal: AJNR. American journal of neuroradiology (AJNR Am J Neuroradiol) Vol. 37 Issue 10 Pg. 1920-1924 (Oct 2016) ISSN: 1936-959X [Electronic] United States
• PMID: 27365326 (Publication Type: Journal Article)
• Copyright: © 2016 by American Journal of Neuroradiology.