Abstract | BACKGROUND: METHODS: Analysis of patch test data during 1999 to 2013 was done. Patients with cement-induced chromate OACD filled the Dermatology Life Quality Index, graded 1 to 5. RESULTS: Of 4846 consecutive patients who were patch tested, 146 (3%) were chromate-sensitive. Of 46 (31.5%) who presented with chromate OACD, 27 (59%) had cement-induced chromate OACD. The proportion of chromate-sensitive patients with clinically relevant cement exposure increased from 7.7% in 2002 to 2004 to 28.7% in 2011 to 2013 (P = 0.04). The median age of presentation was younger than for other chromate-sensitive patients (32 vs 42 years). Hand eczema (88.9%) was the most frequent clinical presentation. Of the 27 with cement-induced chromate OACD, 21 (77.8%) had ongoing dermatitis at the time of the review. Although 14/27 (51.9%) changed their occupation to avoid exposure to cement, symptoms persisted in 9/14 (64.3%). Prolonged exposure to cement before development of symptoms was associated with chronicity. All the symptomatic patients experienced at least a moderate effect on their quality of life (grade 3 or higher on the Dermatology Life Quality Index). CONCLUSIONS: We recommend the adoption of the European legislation in Israel, to reduce the prevalence of chromate OACD from cement.
|
Authors | Khalaf Kridin, Reuven Bergman, Mogher Khamaisi, Shira Zelber-Sagi, Sara Weltfriend |
Journal | Dermatitis : contact, atopic, occupational, drug
(Dermatitis)
2016 Jul-Aug
Vol. 27
Issue 4
Pg. 208-14
ISSN: 2162-5220 [Electronic] United States |
PMID | 27331340
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Child
- Child, Preschool
- Chromates
(adverse effects)
- Dermatitis, Allergic Contact
(epidemiology, etiology)
- Dermatitis, Occupational
(epidemiology, etiology)
- Female
- Humans
- Israel
(epidemiology)
- Male
- Middle Aged
- Young Adult
|