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Strategies and Methods for the Synthesis of Anticancer Natural Product Neopeltolide and its Analogs.

Abstract
Neopeltolide, isolated in 2007, with its novel structural features and potent anti cancer cell proliferation activity, has attracted a tremendous amount of synthetic efforts. This review briefly and chronologically summarizes each of the synthesis with the main focus on the strategies and methodologies for the construction of its cis-tetrahydropyran-containing macrolactone core.
AuthorsYu Bai, Mingji Dai
JournalCurrent organic chemistry (Curr Org Chem) 2015 Vol. 19 Issue 10 Pg. 871-885 ISSN: 1385-2728 [Print] Netherlands
PMID27182194 (Publication Type: Journal Article)

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