[A Case of Chordoma of the Sacrum Treated with Pazopanib].

Abstract

A-70-year-old man with chordoma of the sacrum was treated with pazopanib (initially 400 mg/day, upto 800 mg/day). After 2 months of treatment, a significant tumor reduction was achieved and the patient was able to sit down easily. Therefore, the pazopanib therapy was continued. He had 14 months of progression-free survival.

• Authors: Akihiro Shinji, Satomi Okada, Toshitsugu Nakamura
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 43 Issue 2 Pg. 267-9 (Feb 2016) ISSN: 0385-0684 [Print] Japan
• PMID: 27067697 (Publication Type: Case Reports, Journal Article)

Chemical References

• Angiogenesis Inhibitors
• Indazoles
• Pyrimidines
• Sulfonamides
• pazopanib

Topics

• Aged
• Angiogenesis Inhibitors (therapeutic use)
• Biopsy
• Chordoma (drug therapy)
• Humans
• Indazoles
• Male
• Pyrimidines (therapeutic use)
• Quality of Life
• Sacrum (pathology)
• Spinal Neoplasms (drug therapy)
• Sulfonamides (therapeutic use)