This study evaluates clinically the effect of
propolis paste on healing of cutaneous
wound in dogs. Under
general anesthesia and complete aseptic conditions, two full thickness skin
wounds (3 cm diameter) were created in each side of the chest in five dogs, one dorsal and one ventral, with 10 cm between them. These
wounds were randomly allocated into two groups, control group (10
wounds) and
propolis group (10
wounds). Both groups were represented in each dog. The
wounds were cleaned with
normal saline solution and dressed with
macrogol ointment in control group and
propolis paste in
propolis group, twice daily till complete wound healing. Measurement of the
wound area (cm(2)) was monitored planimetrically at 0, 7, 14, 21, 28, and 35 days after injury. The data were analyzed statistically. The results revealed a significant reduction in the
wound surface area in the
propolis group after 14 and 21 days compared to control group. The
wound reepithelization, contraction, and total wound healing were faster in
propolis group than in control group during five weeks of study. In conclusion,
propolis paste has a positive impact on cutaneous wound healing and it may be suggested for treating various types of
wounds in animals.