A case of amylase-producing small cell lung cancer.

Abstract

OBJECTIVES:

To assess the relationship between amylase level and small cell lung cancer in a patient with hyperamylasemia of non-pancreatic disease.

DESIGN AND METHODS:

Case report with correlation analysis between hyperamylasemia and small cell lung cancer while considering immunohistochemistry study and response to chemotherapy.

RESULTS:

We observed a strong correlation between amylase levels and small cell lung cancer. Immunohistochemistry findings suggested that amylase was produced by the lung cancer in this case.

CONCLUSIONS:

Amylase can be considered as a tumor marker reflecting response to chemotherapy and disease relapse.

• Authors: Huaiyu Wang, Qing Wu
• Journal: Clinical biochemistry (Clin Biochem) Vol. 49 Issue 7-8 Pg. 613-6 (May 2016) ISSN: 1873-2933 [Electronic] United States
• PMID: 26779994 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2016 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

Chemical References

• Antineoplastic Agents
• Biomarkers, Tumor
• Amylases

Topics

• Amylases (analysis)
• Antineoplastic Agents (therapeutic use)
• Biomarkers, Tumor (analysis)
• Drug Monitoring
• Humans
• Hyperamylasemia (diagnosis, etiology, metabolism)
• Immunoenzyme Techniques
• Lung Neoplasms (complications, enzymology)
• Male
• Middle Aged
• Prognosis
• Small Cell Lung Carcinoma (complications, drug therapy, enzymology)