Tunneled Pleural Catheter Placement with and without Talc Poudrage for Treatment of Pleural Effusions Due to Congestive Heart Failure.

Abstract

RATIONALE:

There is a paucity of evidence regarding the role of tunneled pleural catheters in pleural effusions caused by congestive heart failure that is refractory to medical management.

OBJECTIVES:

The aim of this study was to assess the feasibility of tunneled pleural catheter drainage for treatment of refractory pleural effusions associated with congestive heart failure, either when used alone or with concomitant talc pleurodesis performed during thoracoscopy.

METHODS:

This was a retrospective cohort study. We identified patients with congestive heart failure and recurrent symptomatic pleural effusions who were treated between 2005 and 2015 by placement of a tunneled pleural catheter. Patients underwent either thoracoscopy followed by talc poudrage and pleural catheter placement (group 1) or catheter insertion alone (group 2).

MEASUREMENTS AND MAIN RESULTS:

Forthy-three catheters were inserted in 36 patients, with 15 placed in group 1 and 28 in group 2. Successful pleurodesis was seen in 80% in group 1 and 25% in group 2. The median time of catheter placement was 11.5 days in group 1 and 66 days in group 2. There was a significant decrease in hospital admissions and pleural interventions after catheter placement compared with before insertion (P < 0.05).

CONCLUSIONS:

This single-center, retrospective study demonstrated the feasibility of catheter placement used alone or with talc poudrage for the treatment of refractory pleural effusions associated with congestive heart failure. The addition of talc poudrage might increase the pleurodesis rate and reduce the days to catheter removal in highly selected patients. Prospective studies on a larger number of patients are warranted to verify the safety and efficacy of this intervention.

• Authors: Adnan Majid, Fayez Kheir, Meghan Fashjian, Sumit Chatterji, Sebastian Fernandez-Bussy, Sebastian Ochoa, George Cheng, Erik Folch
• Journal: Annals of the American Thoracic Society (Ann Am Thorac Soc) Vol. 13 Issue 2 Pg. 212-6 (Feb 2016) ISSN: 2325-6621 [Electronic] United States
• PMID: 26598967 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Talc

Topics

• Aged
• Aged, 80 and over
• Cohort Studies
• Drainage (methods)
• Feasibility Studies
• Female
• Heart Failure (complications)
• Humans
• Male
• Middle Aged
• Pleural Effusion (etiology, therapy)
• Pleurodesis (methods)
• Recurrence
• Retrospective Studies
• Talc (administration & dosage)
• Thoracentesis (methods)
• Thoracoscopy (methods)
• Treatment Outcome