Abstract |
Effective treatment of Clostridium difficile infections demands a shift away from antibiotics towards toxin-neutralizing agents. Work by Bender et al., using a drug that attenuates toxin action in vivo without affecting bacterial survival, demonstrates the exciting potential of small molecules as a new modality in the fight against C. difficile.
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Authors | Greg L Beilhartz, John Tam, Roman A Melnyk |
Journal | Trends in microbiology
(Trends Microbiol)
Vol. 23
Issue 12
Pg. 746-748
(Dec 2015)
ISSN: 1878-4380 [Electronic] England |
PMID | 26547239
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Comment)
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Copyright | Copyright © 2015 Elsevier Ltd. All rights reserved. |
Chemical References |
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Topics |
- Animals
- Anti-Bacterial Agents
(therapeutic use)
- Clostridioides difficile
(isolation & purification)
- Clostridium Infections
(drug therapy)
- Virulence
(drug effects)
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