Zolpidem and Sleep in Pediatric Burn Patients with Attention Deficit/Hyperactivity Disorder.

Abstract

Existing research shows that hospitalized patients, especially pediatric burn patients, are often sleep deprived. A pre-existing diagnosis of attention deficit/hyperactivity disorder (ADHD) further compounds a burn patient's inability to sleep. This retrospective study compared the effectiveness of zolpidem on patients with acute burns with ADHD (n = 23) and patients with acute burns without ADHD (n = 23). Effectiveness was defined based on the need for a change in the sleep medication or an increase in the zolpidem dose during the first 12 days of treatment. This study found that sleep dysfunction was similar in pediatric burn patients with and without a concurrent diagnosis of ADHD. Sixteen (69.6%) patients with and 13 (56.5%) patients without ADHD required a sleep medication change (p = 0.541). Further, while patients with ADHD required a sleep medication change (median = 5 days) sooner than those without ADHD (median = 9 days), it appears that zolpidem is not an effective drug for managing sleep in pediatric burn patients with or without ADHD.

• Authors: Stephanie D Cronin, Michele M Gottschlich, Lacy M Gose, Richard J Kagan
• Journal: Pediatric nursing (Pediatr Nurs) 2015 May-Jun Vol. 41 Issue 3 Pg. 132-4, 140 ISSN: 0097-9805 [Print] United States
• PMID: 26201171 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Hypnotics and Sedatives
• Pyridines
• Zolpidem

Topics

• Attention Deficit Disorder with Hyperactivity (complications)
• Burns (complications, therapy)
• Child
• Female
• Humans
• Hypnotics and Sedatives (therapeutic use)
• Male
• Ohio
• Pyridines (therapeutic use)
• Retrospective Studies
• Sleep Wake Disorders (drug therapy, etiology)
• Treatment Outcome
• Zolpidem