Abstract |
In this issue of Blood, Miraki-Moud et al demonstrate that the majority of acute myeloid leukemias (AMLs) have low expression of argininosuccinate synthetase-1 (ASS1), rendering AML cell lines and primary AML blasts dependent on exogenous arginine and sensitized to arginine deprivation.
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Authors | William Plunkett |
Journal | Blood
(Blood)
Vol. 125
Issue 26
Pg. 3971-2
(Jun 25 2015)
ISSN: 1528-0020 [Electronic] United States |
PMID | 26113532
(Publication Type: Journal Article, Comment)
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Chemical References |
- Antineoplastic Agents
- Polyethylene Glycols
- Hydrolases
|
Topics |
- Animals
- Antineoplastic Agents
(pharmacology)
- Humans
- Hydrolases
(pharmacology)
- Leukemia, Myeloid, Acute
(metabolism)
- Polyethylene Glycols
(pharmacology)
|