Abstract | OBJECTIVE: HYPR flow is a 3D dynamic contrast-enhanced MRA technique providing isotropic sub-millimetre resolution with half-second temporal resolution. We compared HYPR flow and time-resolved imaging of contrast kinetics (TRICKS) MRA for the characterization of cerebral arteriovenous malformations (cAVMs), using catheter DSA as reference. METHODS: Twenty-two patients underwent HYPR flow and TRICKS MRA within 15 days of DSA. HYPR flow and TRICKS datasets were reviewed separately by two readers for image quality, Spetzler-Martin grade, venous ectasia, and deep venous drainage. RESULTS: Image quality was better for HYPR flow than for TRICKS (narrower full width at half maximum; larger arterial diagnostic window; greater number of arterial frames, P ≤ 0.05). Using HYPR flow, inter-reader agreement was excellent for all cAVM characteristics. The agreement with DSA for the overall Spetzler-Martin grade was excellent for HYPR flow (ICC = 0.96 and 0.98, depending on the reader) and TRICKS (ICC = 0.82 and 0.95). In comparison to TRICKS, HYPR flow showed higher concordance with DSA for the identification of venous ectasia and deep venous drainage. CONCLUSION: Owing to an excellent agreement with DSA with respect to depiction of the vascular architecture of cAVMs, HYPR flow could be useful for the non-invasive characterization of cAVMs. KEY POINTS: • Dynamic MRA is used for cerebral AVM depiction and follow-up • HYPR flow is a new, highly-resolved dynamic MRA sequence • HYPR flow provides whole brain coverage • HYPR flow provides excellent agreement with the Spetzler-Martin grade • Compared to TRICKS MRA, HYPR flow improves cerebral AVM characterization.
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Authors | Raphaël Dautry, Myriam Edjlali, Pauline Roca, Cécile Rabrait, Yijing Wu, Kevin Johnson, Olivier Wieben, Denis Trystram, Christine Rodriguez-Régent, Fawaz Alshareef, Patrick Turski, Jean-François Meder, Olivier Naggara, Catherine Oppenheim |
Journal | European radiology
(Eur Radiol)
Vol. 25
Issue 11
Pg. 3230-7
(Nov 2015)
ISSN: 1432-1084 [Electronic] Germany |
PMID | 25916388
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Angiography, Digital Subtraction
(methods)
- Catheterization
(methods)
- Cerebral Angiography
(methods)
- Contrast Media
- Female
- Hemodynamics
(physiology)
- Humans
- Imaging, Three-Dimensional
(methods)
- Intracranial Arteriovenous Malformations
(pathology, physiopathology)
- Kinetics
- Magnetic Resonance Angiography
(methods)
- Male
- Middle Aged
- Prospective Studies
- Young Adult
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