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Overcoming Resistance Without the Risk of Reaction: Use of Afatinib and Panitumumab in Two Cases of Epidermal Growth Factor Receptor--Mutated Non--Small-Cell Lung Cancer With T790M Mutations.

AuthorsEmily H Castellanos, Gabriel Rivera, Heather Wakelee, Leora Horn
JournalClinical lung cancer (Clin Lung Cancer) Vol. 16 Issue 5 Pg. e97-9 (Sep 2015) ISSN: 1938-0690 [Electronic] United States
PMID25842367 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antibodies, Monoclonal
  • Quinazolines
  • Afatinib
  • Panitumumab
  • EGFR protein, human
  • ErbB Receptors
Topics
  • Afatinib
  • Aged
  • Antibodies, Monoclonal (administration & dosage)
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Carcinoma, Non-Small-Cell Lung (drug therapy, genetics, pathology)
  • Drug Resistance, Neoplasm
  • ErbB Receptors (genetics)
  • Female
  • Humans
  • Lung Neoplasms (drug therapy, genetics, pathology)
  • Middle Aged
  • Mutation
  • Panitumumab
  • Quinazolines (administration & dosage)

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