Abstract | OBJECTIVE: METHODS: CT, MRI and clinical features in 16 patients with histologically proven RIEACCs were retrospectively reviewed. There were 2 females and 14 males, with a median age of 52.5 years at the time of diagnosis of RIEACC. Imaging parameters including lesion extent, size, margin, shape, bone destruction, adjacent structure invasion, density/signal intensity, and pattern and degree of enhancement were assessed. Clinical features including clinical staging, histological type, treatment and radiation dose (RD) of primary NPC as well as the histological type, staging of radiation-induced tumour and the latent period between NPC and RIT were recorded. RESULTS: All patients had a single RIEACC. The lesions had a size of 3.5 ± 1.4 cm and were localized (n = 7) or extensive (n = 9). Most of the lesions were partially or ill defined with an irregular shape and had an intermediate density/signal pattern and moderate homogeneous enhancement. The latent period of RIEACCs ranged from 10 to 20 years in nine patients with a RD of 68-70 Gy; from 2 to 10 years in five patients with a RD of 68-74 Gy; and more than 20 years in two patients with a RD of 70 or 72 Gy. CONCLUSION: An external auditory canal (EAC) mass with homogeneous, intermediate CT density or signal intensity in patients with NPC after radiotherapy is highly suggestive of RIEACC, which should be included in the routine surveillance for patients with NPC after radiotherapy. ADVANCES IN KNOWLEDGE:
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Authors | X Zhang, S Bai, H Li, H Hu, X Duan, M Chen, D Wang, Y Chen, F Zhang, J Shen |
Journal | The British journal of radiology
(Br J Radiol)
Vol. 88
Issue 1050
Pg. 20140791
(Jun 2015)
ISSN: 1748-880X [Electronic] England |
PMID | 25827205
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Ear Canal
(radiation effects)
- Ear Neoplasms
(diagnosis, etiology)
- Female
- Humans
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Nasopharyngeal Neoplasms
(radiotherapy)
- Neoplasms, Radiation-Induced
(diagnosis)
- Radiotherapy Dosage
- Retrospective Studies
- Tomography, X-Ray Computed
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