Relationship between duration of prehospital resuscitation and favorable prognosis in ventricular fibrillation.

Abstract

OBJECTIVE:

There appears to be an optimal point in balancing the relative benefits of extending the resuscitation time to obtain return of spontaneous circulation in the prehospital setting and the initiation of therapies such as extracorporeal cardiopulmonary resuscitation (CPR). This study investigated how prehospital CPR duration is related to survival and neurologic outcome in ventricular fibrillation (VF) and tried to find the tolerable time for prehospital resuscitation.

MATERIALS AND METHODS:

Out-of-hospital cardiac arrest patients with VF in Funabashi City, Japan, from January 2009 to December 2013 were reviewed. Resuscitation teams that included physicians were dispatched to incident sites. Survival rate at 24 hours and neurologic outcome at 30 days were analyzed with respect to prehospital CPR duration.

RESULTS:

A total of 172 patients were evaluated. Seventy-three patients were alive at 24 hours. Thirty-four patients had favorable neurologic outcomes after 30 days. Of the 69 patients who required prolonged prehospital CPR (>30 minutes), 6 were alive at 24 hours, and only 1 had a favorable neurologic outcome at 30 days. Logistic regression model showed that both survival rate at 24 hours and neurologic outcome at 30 days deteriorated with the increase in prehospital CPR duration (both P < .001).

CONCLUSION:

The prognosis of out-of-hospital cardiac arrest patients with VF deteriorated with the increase in prehospital CPR duration. Favorable results are less likely especially in cases of prolonged prehospital CPR (>30 minutes). Therefore, it may be necessary to consider transportation to a more definitive treatment facility rather than extending conventional CPR in the prehospital setting.

• Authors: Takahiro Arima, Osamu Nagata, Koji Sakaida, Takeshi Miura, Hiroyuki Kakuchi, Katsuki Ikeda, Tomoya Mizushima, Azusa Takahashi
• Journal: The American journal of emergency medicine (Am J Emerg Med) Vol. 33 Issue 5 Pg. 677-81 (May 2015) ISSN: 1532-8171 [Electronic] United States
• PMID: 25753293 (Publication Type: Journal Article)
• Copyright: Copyright © 2015 Elsevier Inc. All rights reserved.

Topics

• Aged
• Cardiopulmonary Resuscitation (methods)
• Emergency Medical Services (organization & administration)
• Female
• Humans
• Japan (epidemiology)
• Male
• Middle Aged
• Out-of-Hospital Cardiac Arrest (mortality, therapy)
• Survival Rate
• Time Factors
• Treatment Outcome
• Ventricular Fibrillation (mortality, therapy)