Superparamagnetic MFe2O 4 (M = Ni, Co, Zn, Mn) nanoparticles: synthesis, characterization, induction heating and cell viability studies for cancer hyperthermia applications.

Abstract

Superparamagnetic nanoferrites are prepared by simple and one step refluxing in polyol synthesis. The ferrite nanoparticles prepared by this method exhibit particle sizes below 10 nm and high degree of crystallinity. These ferrite nanoparticles are compared by means of their magnetic properties, induction heating and cell viability studies for its application in magnetic fluid hyperthermia. Out of all studied nanoparticles in present work, only ZnFe2O4 and CoFe2O4 MNPs are able to produce threshold hyperthermia temperature. This rise in temperature is discussed in detail in view of their magneto-structural properties. Therefore ZnFe2O4 and CoFe2O4 MNPs with improved stability, magnetic induction heating and cell viability are suitable candidates for magnetic hyperthermia.

• Authors: Sandip Sabale, Vidhya Jadhav, Vishwajeet Khot, Xiaoli Zhu, Meiling Xin, Hongxia Chen
• Journal: Journal of materials science. Materials in medicine (J Mater Sci Mater Med) Vol. 26 Issue 3 Pg. 127 (Mar 2015) ISSN: 1573-4838 [Electronic] United States
• PMID: 25690622 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Cell Line, Tumor
• Hot Temperature
• Humans
• Hyperthermia, Induced
• Magnetics
• Metal Nanoparticles
• Microscopy, Electron, Transmission
• Neoplasms (therapy)
• X-Ray Diffraction