Association of soda consumption with subclinical cardiac remodeling in the Framingham heart study.

Abstract

OBJECTIVE:

Diet soda consumption increases cardiometabolic risk. The aim of this investigation was to assess the relations between self-reported soda consumption and subclinical cardiac remodeling.

METHODS:

We assessed the relations between self-reported soda consumption and left ventricular mass (LVM) and left atrial dimension (LAD) (both standardized within sex) in a sample of middle-aged attendees from the Framingham Heart Offspring cohort examination 5 and 6.

RESULTS:

The overall mean age was 55 years and 59% of the participants were women. Compared to non-consumers (n=1010), soda consumers (n=3192) had greater body weight (mean 86 vs. 82 kg among men, and 70 vs. 67 kg among women). Compared with non-consumers, age- and height-adjusted LAD was increased (standard deviation units) among soda consumers by 0.15 standard error 0.042, (p<0.001) for those drinking >0-7 diet soda (n=1023), -0.010 (0.043, p=0.82) for people drinking >0-7 regular soda (n=907), 0.22 (0.057, p<0.0001) for individuals consuming >7 diet soda (n=372), and 0.20 (0.092, p=0.034) for participants drinking >7 regular soda (n=116) per week. LVM was increased among participants consuming diet soda (p<0.05), but not in regular soda consumers (p>0.05). Upon adjustment for weight, however, all aforementioned associations were attenuated.

CONCLUSION:

The observed associations between soda consumption and LAD or LVM were likely related to the greater body weight of soda drinkers relative to non-drinkers.

• Authors: Charlotte Andersson, Lisa Sullivan, Emelia J Benjamin, Jayashri Aragam, Paul Jacques, Susan Cheng, Ramachandran S Vasan
• Journal: Metabolism: clinical and experimental (Metabolism) Vol. 64 Issue 2 Pg. 208-12 (Feb 2015) ISSN: 1532-8600 [Electronic] United States
• PMID: 25456096 (Publication Type: Journal Article, Observational Study, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2015 Elsevier Inc. All rights reserved.

Chemical References

• Non-Nutritive Sweeteners
• Nutritive Sweeteners

Topics

• Adult
• Aged
• Atrial Remodeling
• Body Weight
• Carbonated Beverages (adverse effects)
• Cohort Studies
• Cross-Sectional Studies
• Echocardiography
• Female
• Humans
• Male
• Massachusetts (epidemiology)
• Middle Aged
• Non-Nutritive Sweeteners (adverse effects)
• Nutritive Sweeteners (adverse effects)
• Risk Factors
• Self Report
• Severity of Illness Index
• Ventricular Dysfunction, Left (diagnostic imaging, epidemiology, etiology, physiopathology)
• Ventricular Remodeling