[The prevalence and relevant factors of hyperglycemia in AIDS patients receiving antiretroviral therapy in a single center].

Abstract

OBJECTIVE:

To investigate the prevalence of hyperglycemia and its associated factors in AIDS patients receiving antiretroviral therapy (ART).

METHODS:

A cross-sectional survey was conducted to obtain the prevalence of hyperglycemia among AIDS patients in a single center. Univariate and multivariate non-conditional logistic regression analysis were used to determine influencing factors of hyperglycemia.

RESULTS:

A total of 504 AIDS patients participated in the survey, who have received ART for at least three months. The prevalence of hyperglycemia was 15.7%. Multivariate analysis showed that age (OR = 1.03, 95%CI 1.00-1.05), family history of diabetes (OR = 2.70, 95%CI 1.55-4.69), overweight (OR = 2.13, 95%CI 1.24-3.67), nadir CD4 cell counts 50-199 cells/µl (OR = 1.95, 95%CI 1.08-3.51) and less than 50 cells/µl (OR = 2.95, 95%CI 1.47-5.91) were relevant factors associated with hyperglycemia.

CONCLUSIONS:

Blood glucose should be monitored regularly in AIDS patients receiving ART , especially among patients with old age, family history of diabetes, overweight and nadir CD4 T cell counts less than 200 cells/µl.

• Authors: Wei Cheng, Yasong Wu, Zhihui Dou, Ye Ma, Lijun Sun, Zaicun Li, Hao Wu, Fujie Zhang
• Journal: Zhonghua nei ke za zhi (Zhonghua Nei Ke Za Zhi) Vol. 53 Issue 6 Pg. 446-9 (Jun 2014) ISSN: 0578-1426 [Print] China
• PMID: 25146511 (Publication Type: Journal Article)

Topics

• Acquired Immunodeficiency Syndrome (complications, drug therapy)
• CD4 Lymphocyte Count
• CD4-Positive T-Lymphocytes
• Cross-Sectional Studies
• Diabetes Mellitus
• Humans
• Hyperglycemia (epidemiology, etiology)
• Logistic Models
• Multivariate Analysis
• Prevalence