Ex vivo biomechanical comparison of V-LOC 180® absorbable wound closure device and standard polyglyconate suture for diaphragmatic herniorrhaphy in a canine model.

Abstract

OBJECTIVE:

To compare 2-0 polyglyconate barbed suture (V-LOC™ 180 Absorbable Wound Closure Device, Covidien, Mansfield, MA) to standard 2-0 monofilament absorbable polyglyconate suture (Maxon™, Covidien) for maximum load to failure and failure mode when used to appose standardized defects in canine diaphragm muscle.

STUDY DESIGN:

Randomized, cadaveric ex vivo mechanical testing.

SAMPLE POPULATION:

Canine cadaveric hemi-diaphragmatic specimens (n = 32 pairs).

METHODS:

Thirty-two cadaveric diaphragm specimens were collected and divided to obtain 64 muscle specimens (9 cm × 4 cm). Paired specimens were bisected in the midpoint of their 9 cm length in the direction of the muscle fibers and apposed using either 2-0 polyglyconate or 2-0 barbed polyglyconate (V-LOC™ 180 Absorbable Wound Closure Device) in a simple continuous pattern. Increasing tension was applied perpendicular to the suture line until specimen failure. Failure mode and maximum load to failure were recorded for each specimen.

RESULTS:

Mean ± SD failure load of simulated herniorrhaphies performed with barbed polyglyconate suture (54.5 ± 10.27 N) was not significantly different than repair with polyglyconate (56.9 ± 10.87 N). Failure mode for both construct types was suture tear out rather than suture failure.

CONCLUSIONS:

Clinical application of 2-0 barbed polyglyconate suture can be considered as an alternative to the use of 2-0 polyglyconate for diaphragmatic herniorrhaphy.

• Authors: Megan M Templeton, Alexander I Krebs, Karl H Kraus, Cheryl S Hedlund
• Journal: Veterinary surgery : VS (Vet Surg) Vol. 44 Issue 1 Pg. 65-9 (Jan 2015) ISSN: 1532-950X [Electronic] United States
• PMID: 24962167 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © Copyright 2014 by The American College of Veterinary Surgeons.

Chemical References

• Polymers
• polyglyconate

Topics

• Animals
• Biomechanical Phenomena
• Cadaver
• Dogs (surgery)
• Herniorrhaphy (methods, veterinary)
• Models, Animal
• Polymers
• Sutures