Abstract | OBJECTIVE: METHODS: We performed an observational study on VLBW infants admitted to the NICU of Padua. Each patient with HCAM was matched with one control without HCAM. All infants underwent hearing screening before discharge by means of automated transient-evoked otoacustic emissions and automated auditory brainstem responses, which were repeated at 3 and 6 months of age with tympanometry measurement. Incidence of SNHL at 6 months of age was compared in the 2 groups and risk factors for hearing loss were studied. RESULTS: Two of 77 (2.6%) newborns with HCAM e 6/73 (8.2%) without it presented SNHL at 6 months of corrected age (p = 0.16). Multivariable logistic regression analysis identified surgical ligation of patent ductus arteriosus (PDA) as independent predictors of SNHL (OR: 5.75, 95% CI 1.34-24.84, p = 0.02), whereas the effect of HCAM on SNHL was only near to statistical significance level. CONCLUSIONS: Surgical ligation of PDA is associated with an increased risk of SNHL in VLBW infants, regardless of HCAM.
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Authors | Stefania Vedovato, Angela Lo Iacono, Carla Morando, Agnese Suppiej, Eva Orzan, Daniele Trevisanuto, Silvia Visentin, Francesco Cavallin, Silvia Chiarelli, Vincenzo Zanardo |
Journal | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
(J Matern Fetal Neonatal Med)
Vol. 28
Issue 8
Pg. 895-9
(May 2015)
ISSN: 1476-4954 [Electronic] England |
PMID | 24949929
(Publication Type: Journal Article, Observational Study)
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Topics |
- Case-Control Studies
- Chorioamnionitis
(diagnosis)
- Female
- Follow-Up Studies
- Hearing Loss, Sensorineural
(diagnosis, etiology)
- Humans
- Infant
- Infant, Newborn
- Infant, Premature
- Infant, Premature, Diseases
(diagnosis, etiology)
- Infant, Very Low Birth Weight
- Logistic Models
- Male
- Pregnancy
- Prospective Studies
- Risk Factors
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