Biological therapies for spondyloarthritis.

Abstract

Biological therapies and new imaging techniques have changed the therapeutic and diagnostic approach to spondyloarthritis. In patients with axial spondyloarthritis, tumor necrosis factor α (TNFα) inhibitor treatment is currently the only effective therapy in patients for whom conventional therapy with nonsteroidal anti-inflammatory drugs (NSAIDs) has failed. TNFα inhibitor treatment is more effective in preventing articular damage in peripheral joints than in axial ones. It is important to treat patients at an early stage of disease to reduce disease progression; moreover it is necessary to identify causes of therapy inefficacy in preventing joint damage in the axial subset.

• Authors: Vincenzo Bruner, Mariangela Atteno, Angelo Spanò, Raffaele Scarpa, Rosario Peluso
• Journal: Therapeutic advances in musculoskeletal disease (Ther Adv Musculoskelet Dis) Vol. 6 Issue 3 Pg. 92-101 (Jun 2014) ISSN: 1759-720X [Print] England
• PMID: 24891880 (Publication Type: Journal Article, Review)