Abstract | OBJECTIVES: SETTING: METHODS: Implementational and operational costs of a new expanded mass spectrometry-based newborn screening programme were estimated. Data on various medical expenditures for the mild and severe phenotypic subtypes were gathered from a case cohort diagnosed with PTPS deficiency from 2001 to 2009. Local incidence from a previously published study was used. RESULTS: Implementation and operational costs of an expanded newborn screening programme in Hong Kong were estimated at HKD 10,473,848 (USD 1,342,801) annually. Assuming a birthrate of 50,000 per year and an incidence of 1 in 29,542 live births, the medical costs and adjusted loss of workforce per year would be HKD 20,773,207 (USD 2,663,232). Overall the annual savings from implementing the programme would be HKD 9,632,750 (USD 1,234,968). CONCLUSIONS: Our estimates show that implementation of an expanded newborn screening programme in Hong Kong is cost-effective, with a significant annual saving for public expenditure.
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Authors | Hencher Han-Chih Lee, Chloe Miu Mak, Grace Wing-Kit Poon, Kar-Yin Wong, Ching-Wan Lam |
Journal | Journal of medical screening
(J Med Screen)
Vol. 21
Issue 2
Pg. 61-70
(Jun 2014)
ISSN: 1475-5793 [Electronic] England |
PMID | 24803483
(Publication Type: Journal Article)
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Copyright | © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav. |
Chemical References |
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Topics |
- Cost-Benefit Analysis
- Female
- Hong Kong
(epidemiology)
- Humans
- Incidence
- Infant, Newborn
- Male
- Neonatal Screening
(economics)
- Phenylketonurias
(economics, epidemiology, prevention & control)
- Phosphorus-Oxygen Lyases
(deficiency, economics)
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