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Idelalisib has activity in mantle cell lymphoma.

Abstract
The PI3Kδ inhibitor idelalisib was effective in heavily pretreated patients with mantle cell lymphoma.
Authors
JournalCancer discovery (Cancer Discov) Vol. 4 Issue 5 Pg. OF8 (May 2014) ISSN: 2159-8290 [Electronic] United States
PMID24795031 (Publication Type: Journal Article)
Chemical References
  • Antineoplastic Agents
  • Phosphoinositide-3 Kinase Inhibitors
  • Purines
  • Quinazolinones
  • idelalisib
Topics
  • Antineoplastic Agents (administration & dosage, therapeutic use)
  • Clinical Trials, Phase I as Topic
  • Dose-Response Relationship, Drug
  • Humans
  • Lymphoma, Mantle-Cell (drug therapy, pathology)
  • Phosphoinositide-3 Kinase Inhibitors
  • Purines (administration & dosage, therapeutic use)
  • Quinazolinones (administration & dosage, therapeutic use)

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