Asymptomatic bacteriuria in preadolescent girls.

Abstract

BACKGROUND:

The detection of asymptomatic bacteriuria in preadolescent girls may be important due to its effects on subsequent pregnancies.

OBJECTIVE:

To describe the prevalence of asymptomatic bacteriuria in preadolescent girls and the value of the nitrite test for screening.

MATERIAL AND METHODS:

Cross-sectional study in girls aged 9 to 13 years. Bacteriuria was defined as the growth of > 100,000 CFU/mL in 2 consecutive urine specimens.

RESULTS:

Three hundred and twenty seven girls were included. Asymptomatic bacteriuria was found in 7 girls, so the prevalence was 2.1% (95% CI, 1 to 4.4%). Escherichia coli was the isolated agent in all the cases. Focused interrogatory found history of urinary symptoms in 6 girls. The utility values of the nitrite test were: sensitivity, 1; specificity, 0.9; positive likelihood ratio, 10; and negative predictive value, 1.

CONCLUSIONS:

The prevalence of asymptomatic bacteriuria in preadolescent girls in this Mexican study is similar to the one reported internationally; it is reasonable to consider its early detection to avoid its effects on future pregnancies. Nitrite test seems to be good for screening.

• Authors: Alejandro E Macías, Gloria P Trujillo, Luis A Dubey, Omar A Ramírez, Virginia Arreguín, Juan M Muñoz, Juan H Macías, Juan L Mosqueda
• Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion (Rev Invest Clin) 2013 Sep-Oct Vol. 65 Issue 5 Pg. 399-402 ISSN: 0034-8376 [Print] Mexico
• PMID: 24687339 (Publication Type: Journal Article)

Chemical References

• Nitrites
• Reagent Strips
• Nitrofurantoin

Topics

• Adolescent
• Age of Onset
• Asymptomatic Diseases
• Bacteriuria (diagnosis, epidemiology, urine)
• Child
• Cross-Sectional Studies
• Early Diagnosis
• Escherichia coli (isolation & purification)
• Escherichia coli Infections (diagnosis, epidemiology, urine)
• Female
• Humans
• Mass Screening
• Nitrites (urine)
• Nitrofurantoin (therapeutic use)
• Predictive Value of Tests
• Prevalence
• Puberty
• Reagent Strips
• Treatment Failure