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Effectiveness of a new fluoride varnish for caries prevention in pre-school children.

AbstractOBJECTIVE:
To investigate the effectiveness of a new fluoride varnish (Clinpro White Varnish, 3MEspe, Seefeld, Germany) with regard to the caries incidence within a 2-year period
STUDY DESIGN:
A non-randomized sample of 400 children from the Kyffhäuser district (Thuringia, Germany) was divided into a fluoride group (FG, biannual application of fluoride varnish) and control group (CG, no intervention). (Non-)cavitated caries lesions were recorded using World Health Organization (WHO) and Universal Visual Scoring System (UniViSS) criteria. Parents were given questionnaires to gather information about their socio-economic status (SES). Non-parametric methods and binomial logistic regression were used for data analysis.
RESULTS:
There was a significant increase in caries incidence in both groups. The number of non-cavitated carious lesions was significantly lower in the FG (mean 2.2; sd 2.3) compared with the CG (mean 2.9; sd 1.9). Initial statistical analysis revealed that fluoride varnish might prevent non-cavitated carious lesions. When including SES as a confounder into regression model, potential preventive effect was lost.
CONCLUSIONS:
This study underlines the importance of the multi-factorial etiology of caries and illustrates that the effectiveness of biannual fluoride varnish application was evident in non-cavitated carious lesions only.
AuthorsVinay Pitchika, Claudia J Kokel, Jana Andreeva, Alexander Crispin, Reinhard Hickel, Jan Kühnisch, Roswitha Heinrich-Weltzien
JournalThe Journal of clinical pediatric dentistry (J Clin Pediatr Dent) Vol. 38 Issue 1 Pg. 7-12 ( 2013) ISSN: 1053-4628 [Print] Singapore
PMID24579275 (Publication Type: Controlled Clinical Trial, Journal Article)
Chemical References
  • Cariostatic Agents
  • Fluorides, Topical
Topics
  • Cariostatic Agents (therapeutic use)
  • Child, Preschool
  • DMF Index
  • Dental Caries (epidemiology, etiology, pathology, prevention & control)
  • Dental Cavity Lining
  • Fluorides, Topical (therapeutic use)
  • Humans
  • Incidence
  • Logistic Models
  • Longitudinal Studies
  • Prevalence
  • Social Class
  • Statistics, Nonparametric
  • Surveys and Questionnaires
  • Time Factors

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