[Analysis of risk factors associated with metastasis of lymph node along superior mesenteric vein in patients with gastric cancer].

Abstract

OBJECTIVE:

To investigate the risk factors associated with metastasis of lymph node along superior mesenteric vein (No.14v) in gastric cancer.

METHODS:

Clinicopathological data of 70 gastric cancer patients undergoing gastrectomy with No.14v dissection between September 2010 and October 2011 in the Gulou Hospital, Nanjing University School of Medicine were analyzed retrospectively. Associated factors of No.14v lymph nodes metastasis were investigated.

RESULTS:

Of 70 cases, positive No.14v lymph node metastasis was found in 8 cases (11.4%). Univariate analysis showed that the No.14v metastasis was associated with tumor location (P=0.019), tumor size (P=0.004), depth of invasion (P=0.001), TNM staging (P=0.006), and other lymph node group metastasis (all P<0.05), and was not associated with age, gender, Borrmann classification, Lauren classification or histological type (all P>0.05). Multivariate analysis revealed that lntra-pyloric lymph nodes (No.6) metastasis was an independent risk factor of No.14v metastasis (P<0.05). The predictive accuracy was 94.3% (66/70) and false-negative rate was 1.7% (1/60) for No.6 lymph node metastasis.

CONCLUSION:

No.6 lymph node metastasis status can predict the metastasis of No.14v more accurately.

• Authors: Ruohua Chen, Hao Wang, Meng Wang, Wenxian Guan
• Journal: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery (Zhonghua Wei Chang Wai Ke Za Zhi) Vol. 17 Issue 2 Pg. 155-7 (Feb 2014) ISSN: 1671-0274 [Print] China
• PMID: 24577771 (Publication Type: Journal Article)

Topics

• Gastrectomy
• Humans
• Lymph Node Excision
• Lymph Nodes
• Lymphatic Metastasis
• Mesenteric Veins (pathology)
• Neoplasm Staging
• Retrospective Studies
• Risk Factors
• Stomach Neoplasms (pathology, surgery)