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Phosphatidylserine exposure, microparticle formation and mitochondrial depolarisation in Glanzmann thrombasthenia platelets.

AuthorsHong Wang, K W Annie Bang, Victor S Blanchette, Alan T Nurden, Margaret L Rand
JournalThrombosis and haemostasis (Thromb Haemost) Vol. 111 Issue 6 Pg. 1184-6 (Jun 2014) ISSN: 2567-689X [Electronic] Germany
PMID24477274 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • ITGA2B protein, human
  • Integrin alpha2
  • Phosphatidylserines
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Thrombin
Topics
  • Blood Platelets (metabolism, pathology)
  • Case-Control Studies
  • Cell-Derived Microparticles (metabolism, pathology)
  • Child
  • Humans
  • Integrin alpha2 (blood, genetics)
  • Membrane Potential, Mitochondrial
  • Mutation
  • Phosphatidylserines (blood)
  • Platelet Glycoprotein GPIIb-IIIa Complex (genetics, metabolism)
  • Thrombasthenia (blood)
  • Thrombin (metabolism)

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