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Staphylococcus aureus osteomyelitis: bad to the bone.

Abstract
Osteomyelitis is a debilitating bone infection often caused by the bacterial pathogen Staphylococcus aureus. In this issue, Cassat et al. (2013) develop a high-resolution microcomputed tomography (microCT) method to visualize bone remodeling during S. aureus infection and discover that the metalloprotease aureolysin plays a critical role in modulating osteomyelitis pathogenesis.
AuthorsMichael E Olson, Alexander R Horswill
JournalCell host & microbe (Cell Host Microbe) Vol. 13 Issue 6 Pg. 629-31 (Jun 12 2013) ISSN: 1934-6069 [Electronic] United States
PMID23768487 (Publication Type: Journal Article, Comment)
CopyrightCopyright © 2013 Elsevier Inc. All rights reserved.
Chemical References
  • Bacterial Proteins
  • Virulence Factors
  • Metalloendopeptidases
  • aureolysin
Topics
  • Animals
  • Bacterial Proteins (metabolism)
  • Bone Remodeling
  • Metalloendopeptidases (metabolism)
  • Osteomyelitis (pathology)
  • Staphylococcal Infections (pathology)
  • Staphylococcus aureus (pathogenicity)
  • Virulence Factors (metabolism)

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