[Efficacy of pathogenetic therapy in patients with acute gastrointestinal infections using succinic acid derivatives (reamberin)].

Abstract

Comparative study of efficacy of the official therapy of acute gastro-intestinal infections (65 patients) and a complex therapy using a succinic acid derivative reamberin (71 patients) has been carried out. It is established that the introduction of reamberin into infusion therapy in patients with acute gastro-intestinal infections leads to a faster reduction of basic symptoms of intoxication and gastroenteritis, normalization of leukocyte intoxication index, and correction of basic indices of thrombocytes aggregation. These results allow reamberin 1.5% infusion to be recommended for the treatment of patients with acute gastro-intestinal infections.

• Authors: E O Tikhonova, E P Liapina, A A Shul'diakov
• Journal: Eksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) Vol. 76 Issue 1 Pg. 11-3 ( 2013) ISSN: 0869-2092 [Print] Russia (Federation)
• PMID: 23461009 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Antioxidants
• Endotoxins
• Reamberin
• Succinates
• Meglumine

Topics

• Acute Disease
• Adolescent
• Adult
• Antioxidants (pharmacology, therapeutic use)
• Bacterial Infections (blood, drug therapy, microbiology)
• Blood Platelets (drug effects)
• Endotoxins (antagonists & inhibitors, blood)
• Female
• Gastrointestinal Tract (drug effects, microbiology)
• Humans
• Leukocytes (drug effects)
• Male
• Meglumine (analogs & derivatives, pharmacology, therapeutic use)
• Middle Aged
• Platelet Aggregation (drug effects)
• Succinates (pharmacology, therapeutic use)
• Treatment Outcome