[Syphilis].

Abstract

Syphilis is back since 2000. Early syphilis comprises primary syphilis, secondary syphilis and early latent syphilis (less than 1 year duration). During early phases of syphilis, patients are more contagious and neurologic complications are rare. Early neurosyphilis are mostly represented by uveitis or cranial nerves lesions. Treatment of non-neurologic syphilis are based on intramusculary injection of benzathine-penicilline G: one injection in case of early syphilis, three injections in case of late syphilis. The follow-up after treatment is based on clinical evolution and the titer of VDRL. Intravenously infusion of penicillin G is the only treatment recommended for neurosyphilis.

• Authors: Nicolas Dupin, David Farhi
• Journal: Presse medicale (Paris, France : 1983) (Presse Med) Vol. 42 Issue 4 Pt 1 Pg. 446-53 (Apr 2013) ISSN: 2213-0276 [Electronic] France
• Vernacular Title: Syphilis.
• PMID: 23414811 (Publication Type: English Abstract, Journal Article, Review)
• Copyright: Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Chemical References

• Penicillin G
• Penicillin G Benzathine

Topics

• Adult
• Cross-Cultural Comparison
• Cross-Sectional Studies
• Drug Administration Schedule
• Early Diagnosis
• Female
• Humans
• Incidence
• Infant, Newborn
• Infusions, Intravenous
• Injections, Intramuscular
• Male
• Neurosyphilis (diagnosis, drug therapy, epidemiology, transmission)
• Penicillin G (therapeutic use)
• Penicillin G Benzathine (therapeutic use)
• Population Surveillance
• Pregnancy
• Syphilis (diagnosis, drug therapy, epidemiology, transmission)
• Syphilis, Cutaneous (diagnosis, drug therapy, epidemiology, transmission)
• Syphilis, Latent (diagnosis, drug therapy, epidemiology, transmission)