Abstract |
Multiple, pigmented, verrucous, cutaneous lesions in a 2-year-old female cat were pathologically examined. The lesions were linearly arranged on the right side of the body, and had developed along with moderate pruritus since infancy. Histologically, prominent exophytic, papillomatous outgrowths of the epidermis and acanthosis with intense ortho and parakeratotic hyperkeratosis were characteristic of the lesions. Dermal inflammation with mononuclear cells, neutrophils, and eosinophils was also noted. Inclusion bodies, cellular degeneration, and intranuclear viral particles suggesting papillomavirus infection in the keratinocytes were not observed. Papillomavirus antigen and DNA were not detected in the lesions by immunohistochemistry and polymerase chain reaction, respectively. In accordance with these clinical and histopathological features, the cutaneous lesions of the present cat were diagnosed as epidermal nevi, which were consistent with human inflammatory linear verrucous epidermal nevi.
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Authors | Masafumi Sato, Kazuhiro Kariya, Munetaka Matsumoto, Miyuki Itoh, Yoshiyasu Kobayashi, Koji Nishifuji, Junichi Kamiie, Kinji Shirota |
Journal | The Journal of veterinary medical science
(J Vet Med Sci)
Vol. 74
Issue 10
Pg. 1337-9
(Oct 2012)
ISSN: 1347-7439 [Electronic] Japan |
PMID | 22672841
(Publication Type: Case Reports, Journal Article)
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Topics |
- Animals
- Cat Diseases
(pathology, surgery)
- Cats
- Female
- Immunohistochemistry
(veterinary)
- Nevus, Sebaceous of Jadassohn
(pathology, surgery, veterinary)
- Skin Neoplasms
(pathology, surgery, veterinary)
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