Complications of oncologic therapy in the abdomen and pelvis: a review.

Abstract

Cancer therapy has significantly improved in the past few decades with development of various newer classes of cytotoxic chemotherapy as well as novel, molecularly targeted chemotherapy. Similar to chemotherapy, radiotherapy is another important therapeutic option used in the curative and palliative management of various abdominal malignancies. However, both these treatments affect the tumor as well as the normal tissues, leading to significant toxicity. These side effects range from mild to life threatening, and may involve multiple organs. Imaging plays an important role in the early identification of such complications, which may allow more effective patient management. The aim of this article is to discuss and illustrate the wide spectrum of chemotherapy and radiotherapy induced complications in the abdomen and pelvis.

• Authors: Dhakshina Moorthy Ganeshan, Usama Salem, Chitra Viswanathan, Aparna Balachandran, Naveen Garg, Paul Silverman, Priya Bhosale
• Journal: Abdominal imaging (Abdom Imaging) Vol. 38 Issue 1 Pg. 1-21 (Feb 2013) ISSN: 1432-0509 [Electronic] United States
• PMID: 22644726 (Publication Type: Journal Article, Review)

Chemical References

• Antineoplastic Agents

Topics

• Abdomen
• Antineoplastic Agents (adverse effects)
• Blood Vessels (drug effects, radiation effects)
• Diagnostic Imaging
• Digestive System (drug effects, radiation effects)
• Humans
• Neoplasms (drug therapy, radiotherapy)
• Pelvis
• Radiotherapy (adverse effects)
• Urogenital System (drug effects, radiation effects)