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High-dose melphalan with bortezomib as conditioning regimen for autologous stem cell transplant in patients with newly diagnosed multiple myeloma who exhibited at least very good partial response to bortezomib-based induction therapy.

AuthorsWenrong Huang, Jian Li, Honghua Li, Wenying Kang, Jian Bo, Yu Zhao, Chunji Gao, Daobin Zhou, Li Yu
JournalLeukemia & lymphoma (Leuk Lymphoma) Vol. 53 Issue 12 Pg. 2507-10 (Dec 2012) ISSN: 1029-2403 [Electronic] United States
PMID22512306 (Publication Type: Clinical Trial, Phase II, Letter)
Chemical References
  • Boronic Acids
  • Pyrazines
  • Bortezomib
  • Melphalan
Topics
  • Antineoplastic Combined Chemotherapy Protocols (adverse effects, therapeutic use)
  • Bipolar Disorder (etiology)
  • Boronic Acids (administration & dosage, adverse effects)
  • Bortezomib
  • Combined Modality Therapy
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Induction Chemotherapy (adverse effects, methods)
  • Kaplan-Meier Estimate
  • Male
  • Melphalan (administration & dosage, adverse effects)
  • Middle Aged
  • Multiple Myeloma (diagnosis, therapy)
  • Nausea (etiology)
  • Neutropenia (etiology)
  • Pyrazines (administration & dosage, adverse effects)
  • Remission Induction
  • Stem Cell Transplantation (adverse effects, methods)
  • Transplantation Conditioning (adverse effects, methods)
  • Transplantation, Autologous
  • Treatment Outcome

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