Combined elective percutaneous coronary intervention and transapical transcatheter aortic valve implantation.

Abstract

There is no established strategy of how and when to treat coronary artery disease (CAD) in patients referred for transcatheter aortic valve implantation (TAVI). Simultaneous, single-stage treatment of both pathologies is a possible solution. We report our initial results of simultaneously performed transapical TAVI and elective percutaneous coronary interventions (PCI) in high-risk patients with severe aortic valve stenosis. Between April 2008 and July 2011, a total of 419 patients underwent transapical TAVI. Combined elective PCI and TAVI were performed in 46 (11%) patients. Only the most significant coronary lesion or lesions were treated. Technical success of the combined approach was 100%. The mean count of implanted stents per patient was 1.6 ± 1.0 (range, 1-5 stents). The 30-day mortality rates in the PCI and TAVI group was 4.3%. Survival at 12, 24 and 36 months of the PCI and TAVI group 87.1 ± 5.5, 69.7 ± 10.3 and 69.7 ± 10.3%, respectively. The results showed that the single-stage approach with combined elective PCI and TAVI is feasible and safe. It has become our primary choice for treatment of high-risk patients with severe aortic valve stenosis and CAD.

• Authors: Miralem Pasic, Stephan Dreysse, Axel Unbehaun, Semih Buz, Thorsten Drews, Christoph Klein, Giuseppe D'Ancona, Roland Hetzer
• Journal: Interactive cardiovascular and thoracic surgery (Interact Cardiovasc Thorac Surg) Vol. 14 Issue 4 Pg. 463-8 (Apr 2012) ISSN: 1569-9285 [Electronic] England
• PMID: 22232234 (Publication Type: Journal Article)

Topics

• Aged
• Aged, 80 and over
• Angioplasty, Balloon, Coronary (adverse effects, instrumentation, mortality)
• Aortic Valve Stenosis (complications, diagnosis, mortality, therapy)
• Cardiac Catheterization (adverse effects, mortality)
• Coronary Angiography
• Coronary Stenosis (complications, diagnosis, mortality, therapy)
• Feasibility Studies
• Female
• Germany
• Heart Valve Prosthesis Implantation (adverse effects, methods, mortality)
• Humans
• Kaplan-Meier Estimate
• Male
• Severity of Illness Index
• Stents
• Time Factors
• Treatment Outcome