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Congenital and acquired neutropenias consensus guidelines on therapy and follow-up in childhood from the Neutropenia Committee of the Marrow Failure Syndrome Group of the AIEOP (Associazione Italiana Emato-Oncologia Pediatrica).

Abstract
The management of congenital and acquired neutropenias presents some differences according to the type of the disease. Treatment with recombinant human granulocyte-colony stimulating factor (G-CSF) is not standardized and scanty data are available on the best schedule to apply. The frequency and the type of longitudinal controls in patients affected with neutropenias are not usually discussed in the literature. The Neutropenia Committee of the Marrow Failure Syndrome Group (MFSG) of the Associazione Italiana di Emato-Oncologia Pediatrica (AIEOP) elaborated this document following design and methodology formerly approved by the AIEOP board. The panel of experts reviewed the literature on the topic and participated in a conference producing a document that includes recommendations on neutropenia treatment and timing of follow-up.
AuthorsFrancesca Fioredda, Michaela Calvillo, Sonia Bonanomi, Tiziana Coliva, Fabio Tucci, Piero Farruggia, Marta Pillon, Baldassarre Martire, Roberta Ghilardi, Ugo Ramenghi, Daniela Renga, Giuseppe Menna, Anna Pusiol, Angelica Barone, Eleonora Gambineri, Giovanni Palazzi, Gabriella Casazza, Marina Lanciotti, Carlo Dufour, Neutropenia Committee of the Marrow Failure Syndrome Group of the AIEOP (Associazione Italiana Emato-Oncologia Pediatrica)
JournalAmerican journal of hematology (Am J Hematol) Vol. 87 Issue 2 Pg. 238-43 (Feb 2012) ISSN: 1096-8652 [Electronic] United States
PMID22213173 (Publication Type: Journal Article, Practice Guideline)
Chemical References
  • Granulocyte Colony-Stimulating Factor
Topics
  • Antineoplastic Combined Chemotherapy Protocols (pharmacology, therapeutic use)
  • Bone Marrow (drug effects, pathology)
  • Bone Marrow Transplantation
  • Child
  • Consensus
  • Disease Management
  • Drug Administration Schedule
  • Granulocyte Colony-Stimulating Factor (pharmacology, therapeutic use)
  • Humans
  • Neutropenia (classification, pathology, therapy)
  • Transplantation, Autologous
  • Transplantation, Homologous

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