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Management of vaginal agenesis.

Abstract
Rokitansky syndrome and complete androgen insensitivity syndrome are the most common causes of vaginal agenesis. Treatment should be deferred until adolescence to allow informed consent and compliance. The best treatment for vaginal agenesis remains controversial although vaginal dilation therapy is still widely considered the first line treatment because success rates are high and associated risks are low. A variety of surgical options are also available, each with enthusiastic proponents. Long-term outcome studies on most surgical techniques, however, are still lacking and until recently most studies have reported on success rate in terms of anatomical success only, without including sexual function. Moreover, the medical literature lacks prospective comparative outcome studies, meaning that current choice of surgical procedure relies greatly on the surgeon's preference and experience.
AuthorsRola S Nakhal, Sarah M Creighton
JournalJournal of pediatric and adolescent gynecology (J Pediatr Adolesc Gynecol) Vol. 25 Issue 6 Pg. 352-7 (Dec 2012) ISSN: 1873-4332 [Electronic] United States
PMID21872517 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2012 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.
Topics
  • 46, XX Disorders of Sex Development
  • Abnormalities, Multiple (surgery, therapy)
  • Androgen-Insensitivity Syndrome (surgery, therapy)
  • Congenital Abnormalities
  • Dilatation
  • Female
  • Humans
  • Kidney (abnormalities, surgery)
  • Male
  • Mullerian Ducts (abnormalities, surgery)
  • Somites (abnormalities, surgery)
  • Spine (abnormalities, surgery)
  • Time Factors
  • Uterus (abnormalities, surgery)
  • Vagina (abnormalities, surgery)

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