First-in-man transcatheter aortic valve implantation of a 20-mm Edwards SAPIEN XT valve: one step forward for the treatment of patients with severe aortic stenosis and small aortic annulus.

Abstract

We present the case of an 85-year-old woman diagnosed with severe aortic stenosis, porcelain aorta, and a small aortic annulus (17.3 mm), who underwent successful transfemoral transcatheter aortic valve implantation (TAVI) with a 20-mm Edwards SAPIEN XT valve using the NovaFlex+ delivery system. At 1-month follow-up the patient was in NYHA functional class I, and Doppler echocardiography showed a mean residual gradient of 15 mm Hg and trivial paravalvular aortic regurgitation. This case, which shows for the first time the feasibility of TAVI with a 20-mm valve, opens a new avenue for the challenging treatment of patients with aortic stenosis and a small aortic annulus.

• Authors: Josep Rodés-Cabau, Robert DeLarochellière, Eric Dumont
• Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (Catheter Cardiovasc Interv) Vol. 79 Issue 5 Pg. 789-93 (Apr 01 2012) ISSN: 1522-726X [Electronic] United States
• PMID: 21735519 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2011 Wiley Periodicals, Inc.

Topics

• Aged
• Angiography (methods)
• Aortic Valve (diagnostic imaging, pathology)
• Aortic Valve Stenosis (diagnostic imaging, surgery)
• Catheterization (methods)
• Echocardiography, Transesophageal (methods)
• Female
• Follow-Up Studies
• Heart Valve Prosthesis
• Heart Valve Prosthesis Implantation (methods)
• Humans
• Prosthesis Design
• Retreatment
• Risk Assessment
• Severity of Illness Index
• Treatment Outcome