Leaf essential oil of Manekia naranjoana (Piperaceae) from Costa Rica and its cytotoxic activity.

Abstract

The chemical composition of the leaf oil of Manekia naranjoana (C. DC.) Callejas (Piperaceae) from Costa Rica was analyzed by capillary GC/FID and GC/MS. Fifty-five compounds were identified. Major compounds from the leaf oil were beta-pinene (30.6%), alpha-pinene (18.8%), limonene (13.7%), and beta-caryophyllene (6.1%). The oil presented very low toxicity to tumor and non-tumor cell lines, even though it contains components, such as alpha- and beta-pinene, limonene and others, which have been shown to be cytotoxic. This is the first report of the chemical composition of the essential oil obtained from this species.

• Authors: Carlos Chaverri, Cecilia Díaz, José F Cicció
• Journal: Natural product communications (Nat Prod Commun) Vol. 6 Issue 1 Pg. 145-8 (Jan 2011) ISSN: 1934-578X [Print] United States
• PMID: 21366067 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Oils, Volatile

Topics

• Cell Line
• Cell Survival (drug effects)
• Costa Rica
• Humans
• Oils, Volatile (analysis, toxicity)
• Piperaceae (chemistry)
• Plant Leaves (chemistry)