Acute akathisia with quetiapine: A case report and review of literature.

Abstract

Quetiapine is an atypical antipsychotic which has been shown to have greater relative affinity for 5-HT(2A) receptors than for D(2) receptors, due to which it is thought to lead to lower incidence of extrapyramidal symptoms (EPS). However, over the years literature in the form of case reports have accumulated which shows that quetiapine can lead to akathisia, especially in subjects prone to develop EPS. In this study, we report the case of a 22-year-old female who developed akathisia with quetiapine 150 mg/day, which subsided with reduction in dose. We have also reviewed the existing literature with respect to akathisia with quetiapine.

• Authors: Ruchita Shah, Sandeep Grover, Uma Maheshwari, Natasha Kate, Nidhi Malhotra
• Journal: Indian journal of pharmacology (Indian J Pharmacol) Vol. 42 Issue 6 Pg. 416-7 (Dec 2010) ISSN: 1998-3751 [Electronic] India
• PMID: 21189919 (Publication Type: Journal Article)